Categorie
Ketoconazol
Les marques,
Ketoconazol
Analogs
Ketoconazol
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Ketoconazol
Formule chimique
C26H28Cl2N4O4
Ketoconazol
RX lien
http://www.rxlist.com/cgi/generic/ketocon.htm
Ketoconazol
FDA fiche
Ketoconazol
msds (fiche de securite des materiaux)
Ketoconazol
Synthese de reference
J. Heeres et al., US. 4,144,346 (1979)
Ketoconazol
Poids moleculaire
531.43 g/mol
Ketoconazol
Point de fusion
146 oC
Ketoconazol
H2O Solubilite
0,0866 mg / L
Ketoconazol
Etat
Solid
Ketoconazol
LogP
3.651
Ketoconazol
Formes pharmaceutiques
Comprimés; Shampooing; Crème; Suspension
Ketoconazol
Indication
Pour le traitement des éléments suivants infections fongiques systémiques: la candidose chronique candidose cutanéomuqueuse, muguet, candidurie, blastomycose, coccidioïdomycose, histoplasmose, chromomycose et paracoccidioidomycosis.
Ketoconazol
Pharmacologie
Le kétoconazole, comme le clotrimazole, le fluconazole, itraconazole, le miconazole et le, est un agent antifongique imidazole.
Ketoconazol
Absorption
Modérée
Ketoconazol
Toxicite
Hépatotoxicité, DL50 = 86 mg / kg (par voie orale chez le rat)
Ketoconazol
Information pour les patients
Shampoo: May be irritating to mucous membranes of the eyes and contact with this area should be
avoided.
There have been reports that use of the shampoo resulted in removal of the curl from permanently waved hair.
Tablet: Patients should be instructed to report any signs and symptoms which may suggest liver
dysfunction so that appropriate biochemical testing can be done. Such signs and symptoms may include unusual fatigue,
anorexia, nausea and/or vomiting, jaundice, dark urine or pale stools
Ketoconazol
Organismes affectes
Champignons