Categorie
Ketocanazole
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Ketocanazole
Analogs
Ketocanazole
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Ketocanazole
Formule chimique
C26H28Cl2N4O4
Ketocanazole
RX lien
http://www.rxlist.com/cgi/generic/ketocon.htm
Ketocanazole
FDA fiche
Ketocanazole
msds (fiche de securite des materiaux)
Ketocanazole
Synthese de reference
J. Heeres et al., US. 4,144,346 (1979)
Ketocanazole
Poids moleculaire
531.43 g/mol
Ketocanazole
Point de fusion
146 oC
Ketocanazole
H2O Solubilite
0,0866 mg / L
Ketocanazole
Etat
Solid
Ketocanazole
LogP
3.651
Ketocanazole
Formes pharmaceutiques
Comprimés; Shampooing; Crème; Suspension
Ketocanazole
Indication
Pour le traitement des éléments suivants infections fongiques systémiques: la candidose chronique candidose cutanéomuqueuse, muguet, candidurie, blastomycose, coccidioïdomycose, histoplasmose, chromomycose et paracoccidioidomycosis.
Ketocanazole
Pharmacologie
Le kétoconazole, comme le clotrimazole, le fluconazole, itraconazole, le miconazole et le, est un agent antifongique imidazole.
Ketocanazole
Absorption
Modérée
Ketocanazole
Toxicite
Hépatotoxicité, DL50 = 86 mg / kg (par voie orale chez le rat)
Ketocanazole
Information pour les patients
Shampoo: May be irritating to mucous membranes of the eyes and contact with this area should be
avoided.
There have been reports that use of the shampoo resulted in removal of the curl from permanently waved hair.
Tablet: Patients should be instructed to report any signs and symptoms which may suggest liver
dysfunction so that appropriate biochemical testing can be done. Such signs and symptoms may include unusual fatigue,
anorexia, nausea and/or vomiting, jaundice, dark urine or pale stools
Ketocanazole
Organismes affectes
Champignons