Tobramycin
Brand names,
Tobramycin
Analogs
Tobramycin
Brand Names Mixture
Tobramycin
Chemical_Formula
C18H37N5O9
Tobramycin
RX_link
http://www.rxlist.com/cgi/generic2/tobi.htm
Tobramycin
fda sheet
Tobramycin
msds (material safety sheet)
Tobramycin
Synthesis Reference
Y. Takagi et al., Bull. Chem. Soc. Japan 49, 3649 (1976)
Tobramycin
Molecular Weight
467.515 g/mol
Tobramycin
Melting Point
No information avaliable
Tobramycin
H2O Solubility
1E+003 mg/ml
Tobramycin
State
Solid
Tobramycin
LogP
-6.899
Tobramycin
Dosage Forms
Ophthalmic ointment; Powder for solution; Solution for oral inhalation; Ophthalmic solution; Oral solution; IV solution
Tobramycin
Indication
For the treatment of pseudomonas aeruginosa lung infections
Tobramycin
Pharmacology
Tobramycin, an aminoglycoside antibiotic obtained from cultures of Streptomyces tenebrarius, is used in combination with other antibiotics to treat urinary tract infections, gynecologic infections, peritonitis, endocarditis, pneumonia, bacteremia and sepsis, respiratory infections including those associated with cystic fibrosis, osteomyelitis, and diabetic foot and other soft-tissue infections.
Tobramycin
Absorption
No information avaliable
Tobramycin
side effects and Toxicity
LD50=441mg/kg (s.c. in mice)
Tobramycin
Patient Information
Tobramycin
Organisms Affected
Enteric bacteria and other eubacteria