Tobrex
Brand names,
Tobrex
Analogs
Tobrex
Brand Names Mixture
Tobrex
Chemical_Formula
C18H37N5O9
Tobrex
RX_link
http://www.rxlist.com/cgi/generic2/tobi.htm
Tobrex
fda sheet
Tobrex
msds (material safety sheet)
Tobrex
Synthesis Reference
Y. Takagi et al., Bull. Chem. Soc. Japan 49, 3649 (1976)
Tobrex
Molecular Weight
467.515 g/mol
Tobrex
Melting Point
No information avaliable
Tobrex
H2O Solubility
1E+003 mg/ml
Tobrex
State
Solid
Tobrex
LogP
-6.899
Tobrex
Dosage Forms
Ophthalmic ointment; Powder for solution; Solution for oral inhalation; Ophthalmic solution; Oral solution; IV solution
Tobrex
Indication
For the treatment of pseudomonas aeruginosa lung infections
Tobrex
Pharmacology
Tobramycin, an aminoglycoside antibiotic obtained from cultures of Streptomyces tenebrarius, is used in combination with other antibiotics to treat urinary tract infections, gynecologic infections, peritonitis, endocarditis, pneumonia, bacteremia and sepsis, respiratory infections including those associated with cystic fibrosis, osteomyelitis, and diabetic foot and other soft-tissue infections.
Tobrex
Absorption
No information avaliable
Tobrex
side effects and Toxicity
LD50=441mg/kg (s.c. in mice)
Tobrex
Patient Information
Tobrex
Organisms Affected
Enteric bacteria and other eubacteria