Tobramycin Base
Brand names,
Tobramycin Base
Analogs
Tobramycin Base
Brand Names Mixture
Tobramycin Base
Chemical_Formula
C18H37N5O9
Tobramycin Base
RX_link
http://www.rxlist.com/cgi/generic2/tobi.htm
Tobramycin Base
fda sheet
Tobramycin Base
msds (material safety sheet)
Tobramycin Base
Synthesis Reference
Y. Takagi et al., Bull. Chem. Soc. Japan 49, 3649 (1976)
Tobramycin Base
Molecular Weight
467.515 g/mol
Tobramycin Base
Melting Point
No information avaliable
Tobramycin Base
H2O Solubility
1E+003 mg/ml
Tobramycin Base
State
Solid
Tobramycin Base
LogP
-6.899
Tobramycin Base
Dosage Forms
Ophthalmic ointment; Powder for solution; Solution for oral inhalation; Ophthalmic solution; Oral solution; IV solution
Tobramycin Base
Indication
For the treatment of pseudomonas aeruginosa lung infections
Tobramycin Base
Pharmacology
Tobramycin, an aminoglycoside antibiotic obtained from cultures of Streptomyces tenebrarius, is used in combination with other antibiotics to treat urinary tract infections, gynecologic infections, peritonitis, endocarditis, pneumonia, bacteremia and sepsis, respiratory infections including those associated with cystic fibrosis, osteomyelitis, and diabetic foot and other soft-tissue infections.
Tobramycin Base
Absorption
No information avaliable
Tobramycin Base
side effects and Toxicity
LD50=441mg/kg (s.c. in mice)
Tobramycin Base
Patient Information
Tobramycin Base
Organisms Affected
Enteric bacteria and other eubacteria