Tobracin
Brand names,
Tobracin
Analogs
Tobracin
Brand Names Mixture
Tobracin
Chemical_Formula
C18H37N5O9
Tobracin
RX_link
http://www.rxlist.com/cgi/generic2/tobi.htm
Tobracin
fda sheet
Tobracin
msds (material safety sheet)
Tobracin
Synthesis Reference
Y. Takagi et al., Bull. Chem. Soc. Japan 49, 3649 (1976)
Tobracin
Molecular Weight
467.515 g/mol
Tobracin
Melting Point
No information avaliable
Tobracin
H2O Solubility
1E+003 mg/ml
Tobracin
State
Solid
Tobracin
LogP
-6.899
Tobracin
Dosage Forms
Ophthalmic ointment; Powder for solution; Solution for oral inhalation; Ophthalmic solution; Oral solution; IV solution
Tobracin
Indication
For the treatment of pseudomonas aeruginosa lung infections
Tobracin
Pharmacology
Tobramycin, an aminoglycoside antibiotic obtained from cultures of Streptomyces tenebrarius, is used in combination with other antibiotics to treat urinary tract infections, gynecologic infections, peritonitis, endocarditis, pneumonia, bacteremia and sepsis, respiratory infections including those associated with cystic fibrosis, osteomyelitis, and diabetic foot and other soft-tissue infections.
Tobracin
Absorption
No information avaliable
Tobracin
side effects and Toxicity
LD50=441mg/kg (s.c. in mice)
Tobracin
Patient Information
Tobracin
Organisms Affected
Enteric bacteria and other eubacteria