Tenebrimycin
Brand names,
Tenebrimycin
Analogs
Tenebrimycin
Brand Names Mixture
Tenebrimycin
Chemical_Formula
C18H37N5O9
Tenebrimycin
RX_link
http://www.rxlist.com/cgi/generic2/tobi.htm
Tenebrimycin
fda sheet
Tenebrimycin
msds (material safety sheet)
Tenebrimycin
Synthesis Reference
Y. Takagi et al., Bull. Chem. Soc. Japan 49, 3649 (1976)
Tenebrimycin
Molecular Weight
467.515 g/mol
Tenebrimycin
Melting Point
No information avaliable
Tenebrimycin
H2O Solubility
1E+003 mg/ml
Tenebrimycin
State
Solid
Tenebrimycin
LogP
-6.899
Tenebrimycin
Dosage Forms
Ophthalmic ointment; Powder for solution; Solution for oral inhalation; Ophthalmic solution; Oral solution; IV solution
Tenebrimycin
Indication
For the treatment of pseudomonas aeruginosa lung infections
Tenebrimycin
Pharmacology
Tobramycin, an aminoglycoside antibiotic obtained from cultures of Streptomyces tenebrarius, is used in combination with other antibiotics to treat urinary tract infections, gynecologic infections, peritonitis, endocarditis, pneumonia, bacteremia and sepsis, respiratory infections including those associated with cystic fibrosis, osteomyelitis, and diabetic foot and other soft-tissue infections.
Tenebrimycin
Absorption
No information avaliable
Tenebrimycin
side effects and Toxicity
LD50=441mg/kg (s.c. in mice)
Tenebrimycin
Patient Information
Tenebrimycin
Organisms Affected
Enteric bacteria and other eubacteria