Obramycin
Brand names,
Obramycin
Analogs
Obramycin
Brand Names Mixture
Obramycin
Chemical_Formula
C18H37N5O9
Obramycin
RX_link
http://www.rxlist.com/cgi/generic2/tobi.htm
Obramycin
fda sheet
Obramycin
msds (material safety sheet)
Obramycin
Synthesis Reference
Y. Takagi et al., Bull. Chem. Soc. Japan 49, 3649 (1976)
Obramycin
Molecular Weight
467.515 g/mol
Obramycin
Melting Point
No information avaliable
Obramycin
H2O Solubility
1E+003 mg/ml
Obramycin
State
Solid
Obramycin
LogP
-6.899
Obramycin
Dosage Forms
Ophthalmic ointment; Powder for solution; Solution for oral inhalation; Ophthalmic solution; Oral solution; IV solution
Obramycin
Indication
For the treatment of pseudomonas aeruginosa lung infections
Obramycin
Pharmacology
Tobramycin, an aminoglycoside antibiotic obtained from cultures of Streptomyces tenebrarius, is used in combination with other antibiotics to treat urinary tract infections, gynecologic infections, peritonitis, endocarditis, pneumonia, bacteremia and sepsis, respiratory infections including those associated with cystic fibrosis, osteomyelitis, and diabetic foot and other soft-tissue infections.
Obramycin
Absorption
No information avaliable
Obramycin
side effects and Toxicity
LD50=441mg/kg (s.c. in mice)
Obramycin
Patient Information
Obramycin
Organisms Affected
Enteric bacteria and other eubacteria