Obracin
Brand names,
Obracin
Analogs
Obracin
Brand Names Mixture
Obracin
Chemical_Formula
C18H37N5O9
Obracin
RX_link
http://www.rxlist.com/cgi/generic2/tobi.htm
Obracin
fda sheet
Obracin
msds (material safety sheet)
Obracin
Synthesis Reference
Y. Takagi et al., Bull. Chem. Soc. Japan 49, 3649 (1976)
Obracin
Molecular Weight
467.515 g/mol
Obracin
Melting Point
No information avaliable
Obracin
H2O Solubility
1E+003 mg/ml
Obracin
State
Solid
Obracin
LogP
-6.899
Obracin
Dosage Forms
Ophthalmic ointment; Powder for solution; Solution for oral inhalation; Ophthalmic solution; Oral solution; IV solution
Obracin
Indication
For the treatment of pseudomonas aeruginosa lung infections
Obracin
Pharmacology
Tobramycin, an aminoglycoside antibiotic obtained from cultures of Streptomyces tenebrarius, is used in combination with other antibiotics to treat urinary tract infections, gynecologic infections, peritonitis, endocarditis, pneumonia, bacteremia and sepsis, respiratory infections including those associated with cystic fibrosis, osteomyelitis, and diabetic foot and other soft-tissue infections.
Obracin
Absorption
No information avaliable
Obracin
side effects and Toxicity
LD50=441mg/kg (s.c. in mice)
Obracin
Patient Information
Obracin
Organisms Affected
Enteric bacteria and other eubacteria