Tobradistin
Brand names,
Tobradistin
Analogs
Tobradistin
Brand Names Mixture
Tobradistin
Chemical_Formula
C18H37N5O9
Tobradistin
RX_link
http://www.rxlist.com/cgi/generic2/tobi.htm
Tobradistin
fda sheet
Tobradistin
msds (material safety sheet)
Tobradistin
Synthesis Reference
Y. Takagi et al., Bull. Chem. Soc. Japan 49, 3649 (1976)
Tobradistin
Molecular Weight
467.515 g/mol
Tobradistin
Melting Point
No information avaliable
Tobradistin
H2O Solubility
1E+003 mg/ml
Tobradistin
State
Solid
Tobradistin
LogP
-6.899
Tobradistin
Dosage Forms
Ophthalmic ointment; Powder for solution; Solution for oral inhalation; Ophthalmic solution; Oral solution; IV solution
Tobradistin
Indication
For the treatment of pseudomonas aeruginosa lung infections
Tobradistin
Pharmacology
Tobramycin, an aminoglycoside antibiotic obtained from cultures of Streptomyces tenebrarius, is used in combination with other antibiotics to treat urinary tract infections, gynecologic infections, peritonitis, endocarditis, pneumonia, bacteremia and sepsis, respiratory infections including those associated with cystic fibrosis, osteomyelitis, and diabetic foot and other soft-tissue infections.
Tobradistin
Absorption
No information avaliable
Tobradistin
side effects and Toxicity
LD50=441mg/kg (s.c. in mice)
Tobradistin
Patient Information
Tobradistin
Organisms Affected
Enteric bacteria and other eubacteria