Tobrasone
Brand names,
Tobrasone
Analogs
Tobrasone
Brand Names Mixture
Tobrasone
Chemical_Formula
C18H37N5O9
Tobrasone
RX_link
http://www.rxlist.com/cgi/generic2/tobi.htm
Tobrasone
fda sheet
Tobrasone
msds (material safety sheet)
Tobrasone
Synthesis Reference
Y. Takagi et al., Bull. Chem. Soc. Japan 49, 3649 (1976)
Tobrasone
Molecular Weight
467.515 g/mol
Tobrasone
Melting Point
No information avaliable
Tobrasone
H2O Solubility
1E+003 mg/ml
Tobrasone
State
Solid
Tobrasone
LogP
-6.899
Tobrasone
Dosage Forms
Ophthalmic ointment; Powder for solution; Solution for oral inhalation; Ophthalmic solution; Oral solution; IV solution
Tobrasone
Indication
For the treatment of pseudomonas aeruginosa lung infections
Tobrasone
Pharmacology
Tobramycin, an aminoglycoside antibiotic obtained from cultures of Streptomyces tenebrarius, is used in combination with other antibiotics to treat urinary tract infections, gynecologic infections, peritonitis, endocarditis, pneumonia, bacteremia and sepsis, respiratory infections including those associated with cystic fibrosis, osteomyelitis, and diabetic foot and other soft-tissue infections.
Tobrasone
Absorption
No information avaliable
Tobrasone
side effects and Toxicity
LD50=441mg/kg (s.c. in mice)
Tobrasone
Patient Information
Tobrasone
Organisms Affected
Enteric bacteria and other eubacteria