Distobram
Brand names,
Distobram
Analogs
Distobram
Brand Names Mixture
Distobram
Chemical_Formula
C18H37N5O9
Distobram
RX_link
http://www.rxlist.com/cgi/generic2/tobi.htm
Distobram
fda sheet
Distobram
msds (material safety sheet)
Distobram
Synthesis Reference
Y. Takagi et al., Bull. Chem. Soc. Japan 49, 3649 (1976)
Distobram
Molecular Weight
467.515 g/mol
Distobram
Melting Point
No information avaliable
Distobram
H2O Solubility
1E+003 mg/ml
Distobram
State
Solid
Distobram
LogP
-6.899
Distobram
Dosage Forms
Ophthalmic ointment; Powder for solution; Solution for oral inhalation; Ophthalmic solution; Oral solution; IV solution
Distobram
Indication
For the treatment of pseudomonas aeruginosa lung infections
Distobram
Pharmacology
Tobramycin, an aminoglycoside antibiotic obtained from cultures of Streptomyces tenebrarius, is used in combination with other antibiotics to treat urinary tract infections, gynecologic infections, peritonitis, endocarditis, pneumonia, bacteremia and sepsis, respiratory infections including those associated with cystic fibrosis, osteomyelitis, and diabetic foot and other soft-tissue infections.
Distobram
Absorption
No information avaliable
Distobram
side effects and Toxicity
LD50=441mg/kg (s.c. in mice)
Distobram
Patient Information
Distobram
Organisms Affected
Enteric bacteria and other eubacteria