Terazosin
Terazosin Brand names, Terazosin Analogs
Terazosin Brand Names Mixture
- No information avaliable
Terazosin Chemical_Formula
C19H25N5O4
Terazosin RX_link
http://www.rxlist.com/cgi/generic/teraz.htm
Terazosin fda sheet
Terazosin msds (material safety sheet)
Terazosin Synthesis Reference
M. Winn et al., U.S. Pat. 4,026,894 (1977)
Terazosin Molecular Weight
387.433 g/mol
Terazosin Melting Point
273 oC
Terazosin H2O Solubility
29.7mg/mL
Terazosin State
Solid
Terazosin LogP
0.875
Terazosin Dosage Forms
Tablet
Terazosin Indication
For the treatment of symptomatic benign prostatic hyperplasia (BPH) and also for hypertension.
Terazosin Pharmacology
Terazosin, classified as a quinazoline, is similar to doxazosin and prazosin. As an alpha-adrenergic blocking agent, terazosin is used to treat hypertension and benign prostatic hypertrophy (BPH). Terazosin produces vasodilation and reduces peripheral resistance but in general has slight effect on cardiac output. Antihypertensive effect with chronic dosing is usually not accompanied by reflex tachycardia.
Terazosin Absorption
Essentially completely absorbed in man (90% bioavailability).
Terazosin side effects and Toxicity
LD50=259.3mg/kg (i.v. in mice)
Terazosin Patient Information
Terazosin Organisms Affected
Humans and other mammals
