Flumarc
Brand names,
Flumarc
Analogs
Flumarc
Brand Names Mixture
Flumarc
Chemical_Formula
C19H25N5O4
Flumarc
RX_link
http://www.rxlist.com/cgi/generic/teraz.htm
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fda sheet
Flumarc
msds (material safety sheet)
Flumarc
Synthesis Reference
M. Winn et al., U.S. Pat. 4,026,894 (1977)
Flumarc
Molecular Weight
387.433 g/mol
Flumarc
Melting Point
273 oC
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H2O Solubility
29.7mg/mL
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State
Solid
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LogP
0.875
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Dosage Forms
Tablet
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Indication
For the treatment of symptomatic benign prostatic hyperplasia (BPH) and also for hypertension.
Flumarc
Pharmacology
Terazosin, classified as a quinazoline, is similar to doxazosin and prazosin. As an alpha-adrenergic blocking agent, terazosin is used to treat hypertension and benign prostatic hypertrophy (BPH). Terazosin produces vasodilation and reduces peripheral resistance but in general has slight effect on cardiac output. Antihypertensive effect with chronic dosing is usually not accompanied by reflex tachycardia.
Flumarc
Absorption
Essentially completely absorbed in man (90% bioavailability).
Flumarc
side effects and Toxicity
LD50=259.3mg/kg (i.v. in mice)
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Patient Information
Flumarc
Organisms Affected
Humans and other mammals