Hytrinex
Brand names,
Hytrinex
Analogs
Hytrinex
Brand Names Mixture
Hytrinex
Chemical_Formula
C19H25N5O4
Hytrinex
RX_link
http://www.rxlist.com/cgi/generic/teraz.htm
Hytrinex
fda sheet
Hytrinex
msds (material safety sheet)
Hytrinex
Synthesis Reference
M. Winn et al., U.S. Pat. 4,026,894 (1977)
Hytrinex
Molecular Weight
387.433 g/mol
Hytrinex
Melting Point
273 oC
Hytrinex
H2O Solubility
29.7mg/mL
Hytrinex
State
Solid
Hytrinex
LogP
0.875
Hytrinex
Dosage Forms
Tablet
Hytrinex
Indication
For the treatment of symptomatic benign prostatic hyperplasia (BPH) and also for hypertension.
Hytrinex
Pharmacology
Terazosin, classified as a quinazoline, is similar to doxazosin and prazosin. As an alpha-adrenergic blocking agent, terazosin is used to treat hypertension and benign prostatic hypertrophy (BPH). Terazosin produces vasodilation and reduces peripheral resistance but in general has slight effect on cardiac output. Antihypertensive effect with chronic dosing is usually not accompanied by reflex tachycardia.
Hytrinex
Absorption
Essentially completely absorbed in man (90% bioavailability).
Hytrinex
side effects and Toxicity
LD50=259.3mg/kg (i.v. in mice)
Hytrinex
Patient Information
Hytrinex
Organisms Affected
Humans and other mammals