Terazosin hydrochloride
Terazosin hydrochloride Brand names, Terazosin hydrochloride Analogs
Terazosin hydrochloride Brand Names Mixture
- No information avaliable
Terazosin hydrochloride Chemical_Formula
C19H25N5O4
Terazosin hydrochloride RX_link
http://www.rxlist.com/cgi/generic/teraz.htm
Terazosin hydrochloride fda sheet
Terazosin hydrochloride msds (material safety sheet)
Terazosin hydrochloride Synthesis Reference
M. Winn et al., U.S. Pat. 4,026,894 (1977)
Terazosin hydrochloride Molecular Weight
387.433 g/mol
Terazosin hydrochloride Melting Point
273 oC
Terazosin hydrochloride H2O Solubility
29.7mg/mL
Terazosin hydrochloride State
Solid
Terazosin hydrochloride LogP
0.875
Terazosin hydrochloride Dosage Forms
Tablet
Terazosin hydrochloride Indication
For the treatment of symptomatic benign prostatic hyperplasia (BPH) and also for hypertension.
Terazosin hydrochloride Pharmacology
Terazosin, classified as a quinazoline, is similar to doxazosin and prazosin. As an alpha-adrenergic blocking agent, terazosin is used to treat hypertension and benign prostatic hypertrophy (BPH). Terazosin produces vasodilation and reduces peripheral resistance but in general has slight effect on cardiac output. Antihypertensive effect with chronic dosing is usually not accompanied by reflex tachycardia.
Terazosin hydrochloride Absorption
Essentially completely absorbed in man (90% bioavailability).
Terazosin hydrochloride side effects and Toxicity
LD50=259.3mg/kg (i.v. in mice)
Terazosin hydrochloride Patient Information
Terazosin hydrochloride Organisms Affected
Humans and other mammals
