Heitrin
Brand names,
Heitrin
Analogs
Heitrin
Brand Names Mixture
Heitrin
Chemical_Formula
C19H25N5O4
Heitrin
RX_link
http://www.rxlist.com/cgi/generic/teraz.htm
Heitrin
fda sheet
Heitrin
msds (material safety sheet)
Heitrin
Synthesis Reference
M. Winn et al., U.S. Pat. 4,026,894 (1977)
Heitrin
Molecular Weight
387.433 g/mol
Heitrin
Melting Point
273 oC
Heitrin
H2O Solubility
29.7mg/mL
Heitrin
State
Solid
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LogP
0.875
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Dosage Forms
Tablet
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Indication
For the treatment of symptomatic benign prostatic hyperplasia (BPH) and also for hypertension.
Heitrin
Pharmacology
Terazosin, classified as a quinazoline, is similar to doxazosin and prazosin. As an alpha-adrenergic blocking agent, terazosin is used to treat hypertension and benign prostatic hypertrophy (BPH). Terazosin produces vasodilation and reduces peripheral resistance but in general has slight effect on cardiac output. Antihypertensive effect with chronic dosing is usually not accompanied by reflex tachycardia.
Heitrin
Absorption
Essentially completely absorbed in man (90% bioavailability).
Heitrin
side effects and Toxicity
LD50=259.3mg/kg (i.v. in mice)
Heitrin
Patient Information
Heitrin
Organisms Affected
Humans and other mammals