Hytrin
Brand names,
Hytrin
Analogs
Hytrin
Brand Names Mixture
Hytrin
Chemical_Formula
C19H25N5O4
Hytrin
RX_link
http://www.rxlist.com/cgi/generic/teraz.htm
Hytrin
fda sheet
Hytrin
msds (material safety sheet)
Hytrin
Synthesis Reference
M. Winn et al., U.S. Pat. 4,026,894 (1977)
Hytrin
Molecular Weight
387.433 g/mol
Hytrin
Melting Point
273 oC
Hytrin
H2O Solubility
29.7mg/mL
Hytrin
State
Solid
Hytrin
LogP
0.875
Hytrin
Dosage Forms
Tablet
Hytrin
Indication
For the treatment of symptomatic benign prostatic hyperplasia (BPH) and also for hypertension.
Hytrin
Pharmacology
Terazosin, classified as a quinazoline, is similar to doxazosin and prazosin. As an alpha-adrenergic blocking agent, terazosin is used to treat hypertension and benign prostatic hypertrophy (BPH). Terazosin produces vasodilation and reduces peripheral resistance but in general has slight effect on cardiac output. Antihypertensive effect with chronic dosing is usually not accompanied by reflex tachycardia.
Hytrin
Absorption
Essentially completely absorbed in man (90% bioavailability).
Hytrin
side effects and Toxicity
LD50=259.3mg/kg (i.v. in mice)
Hytrin
Patient Information
Hytrin
Organisms Affected
Humans and other mammals