Itrin
Itrin Brand names, Itrin Analogs
Itrin Brand Names Mixture
- No information avaliable
Itrin Chemical_Formula
C19H25N5O4
Itrin RX_link
http://www.rxlist.com/cgi/generic/teraz.htm
Itrin fda sheet
Itrin msds (material safety sheet)
Itrin Synthesis Reference
M. Winn et al., U.S. Pat. 4,026,894 (1977)
Itrin Molecular Weight
387.433 g/mol
Itrin Melting Point
273 oC
Itrin H2O Solubility
29.7mg/mL
Itrin State
Solid
Itrin LogP
0.875
Itrin Dosage Forms
Tablet
Itrin Indication
For the treatment of symptomatic benign prostatic hyperplasia (BPH) and also for hypertension.
Itrin Pharmacology
Terazosin, classified as a quinazoline, is similar to doxazosin and prazosin. As an alpha-adrenergic blocking agent, terazosin is used to treat hypertension and benign prostatic hypertrophy (BPH). Terazosin produces vasodilation and reduces peripheral resistance but in general has slight effect on cardiac output. Antihypertensive effect with chronic dosing is usually not accompanied by reflex tachycardia.
Itrin Absorption
Essentially completely absorbed in man (90% bioavailability).
Itrin side effects and Toxicity
LD50=259.3mg/kg (i.v. in mice)
Itrin Patient Information
Itrin Organisms Affected
Humans and other mammals
