Vasomet
Brand names,
Vasomet
Analogs
Vasomet
Brand Names Mixture
Vasomet
Chemical_Formula
C19H25N5O4
Vasomet
RX_link
http://www.rxlist.com/cgi/generic/teraz.htm
Vasomet
fda sheet
Vasomet
msds (material safety sheet)
Vasomet
Synthesis Reference
M. Winn et al., U.S. Pat. 4,026,894 (1977)
Vasomet
Molecular Weight
387.433 g/mol
Vasomet
Melting Point
273 oC
Vasomet
H2O Solubility
29.7mg/mL
Vasomet
State
Solid
Vasomet
LogP
0.875
Vasomet
Dosage Forms
Tablet
Vasomet
Indication
For the treatment of symptomatic benign prostatic hyperplasia (BPH) and also for hypertension.
Vasomet
Pharmacology
Terazosin, classified as a quinazoline, is similar to doxazosin and prazosin. As an alpha-adrenergic blocking agent, terazosin is used to treat hypertension and benign prostatic hypertrophy (BPH). Terazosin produces vasodilation and reduces peripheral resistance but in general has slight effect on cardiac output. Antihypertensive effect with chronic dosing is usually not accompanied by reflex tachycardia.
Vasomet
Absorption
Essentially completely absorbed in man (90% bioavailability).
Vasomet
side effects and Toxicity
LD50=259.3mg/kg (i.v. in mice)
Vasomet
Patient Information
Vasomet
Organisms Affected
Humans and other mammals