Trazosin HCl
Trazosin HCl Brand names, Trazosin HCl Analogs
Trazosin HCl Brand Names Mixture
- No information avaliable
Trazosin HCl Chemical_Formula
C19H25N5O4
Trazosin HCl RX_link
http://www.rxlist.com/cgi/generic/teraz.htm
Trazosin HCl fda sheet
Trazosin HCl msds (material safety sheet)
Trazosin HCl Synthesis Reference
M. Winn et al., U.S. Pat. 4,026,894 (1977)
Trazosin HCl Molecular Weight
387.433 g/mol
Trazosin HCl Melting Point
273 oC
Trazosin HCl H2O Solubility
29.7mg/mL
Trazosin HCl State
Solid
Trazosin HCl LogP
0.875
Trazosin HCl Dosage Forms
Tablet
Trazosin HCl Indication
For the treatment of symptomatic benign prostatic hyperplasia (BPH) and also for hypertension.
Trazosin HCl Pharmacology
Terazosin, classified as a quinazoline, is similar to doxazosin and prazosin. As an alpha-adrenergic blocking agent, terazosin is used to treat hypertension and benign prostatic hypertrophy (BPH). Terazosin produces vasodilation and reduces peripheral resistance but in general has slight effect on cardiac output. Antihypertensive effect with chronic dosing is usually not accompanied by reflex tachycardia.
Trazosin HCl Absorption
Essentially completely absorbed in man (90% bioavailability).
Trazosin HCl side effects and Toxicity
LD50=259.3mg/kg (i.v. in mice)
Trazosin HCl Patient Information
Trazosin HCl Organisms Affected
Humans and other mammals
