Tenuate
Brand names,
Tenuate
Analogs
Tenuate
Brand Names Mixture
Tenuate
Chemical_Formula
C13H19NO
Tenuate
RX_link
http://www.rxlist.com/cgi/generic3/diethprop.htm
Tenuate
fda sheet
Tenuate
msds (material safety sheet)
Tenuate
Synthesis Reference
No information avaliable
Tenuate
Molecular Weight
205.296 g/mol
Tenuate
Melting Point
No information avaliable
Tenuate
H2O Solubility
No information avaliable
Tenuate
State
No information avaliable
Tenuate
LogP
2.951
Tenuate
Dosage Forms
25 mg tablets and 75 mg controlled-release tablets.
Tenuate
Indication
Used in the management of exogenous obesity as a short-term adjunct (a few weeks) in a regimen of weight reduction based on caloric restriction.
Tenuate
Pharmacology
Diethylpropion is a sympathomimetic stimulant drug marketed as an appetite suppressant. Chemically, it is the N,N-diethyl analog of cathinone. Its mechanism of action is similar to other appetite suppressants such as sibutramine, phentermine and dextroamphetamine.
Tenuate
Absorption
Diethylpropion is rapidly absorbed from the GI tract after oral administration.
Tenuate
side effects and Toxicity
The reported oral LD50 for mice is 600 mg/kg, for rats is 250 mg/kg and for dogs is 225 mg/kg. Manifestation of acute overdosage include restlessness, tremor, hyperreflexia, rapid respiration, confusion, assaultiveness, hallucinations, and panic states.
Tenuate
Patient Information
No information avaliable
Tenuate
Organisms Affected
Humans and other mammals