Amfepramone HCL
Brand names,
Amfepramone HCL
Analogs
Amfepramone HCL
Brand Names Mixture
Amfepramone HCL
Chemical_Formula
C13H19NO
Amfepramone HCL
RX_link
http://www.rxlist.com/cgi/generic3/diethprop.htm
Amfepramone HCL
fda sheet
Amfepramone HCL
msds (material safety sheet)
Amfepramone HCL
Synthesis Reference
No information avaliable
Amfepramone HCL
Molecular Weight
205.296 g/mol
Amfepramone HCL
Melting Point
No information avaliable
Amfepramone HCL
H2O Solubility
No information avaliable
Amfepramone HCL
State
No information avaliable
Amfepramone HCL
LogP
2.951
Amfepramone HCL
Dosage Forms
25 mg tablets and 75 mg controlled-release tablets.
Amfepramone HCL
Indication
Used in the management of exogenous obesity as a short-term adjunct (a few weeks) in a regimen of weight reduction based on caloric restriction.
Amfepramone HCL
Pharmacology
Diethylpropion is a sympathomimetic stimulant drug marketed as an appetite suppressant. Chemically, it is the N,N-diethyl analog of cathinone. Its mechanism of action is similar to other appetite suppressants such as sibutramine, phentermine and dextroamphetamine.
Amfepramone HCL
Absorption
Diethylpropion is rapidly absorbed from the GI tract after oral administration.
Amfepramone HCL
side effects and Toxicity
The reported oral LD50 for mice is 600 mg/kg, for rats is 250 mg/kg and for dogs is 225 mg/kg. Manifestation of acute overdosage include restlessness, tremor, hyperreflexia, rapid respiration, confusion, assaultiveness, hallucinations, and panic states.
Amfepramone HCL
Patient Information
No information avaliable
Amfepramone HCL
Organisms Affected
Humans and other mammals