Amfepramone
Brand names,
Amfepramone
Analogs
Amfepramone
Brand Names Mixture
Amfepramone
Chemical_Formula
C13H19NO
Amfepramone
RX_link
http://www.rxlist.com/cgi/generic3/diethprop.htm
Amfepramone
fda sheet
Amfepramone
msds (material safety sheet)
Amfepramone
Synthesis Reference
No information avaliable
Amfepramone
Molecular Weight
205.296 g/mol
Amfepramone
Melting Point
No information avaliable
Amfepramone
H2O Solubility
No information avaliable
Amfepramone
State
No information avaliable
Amfepramone
LogP
2.951
Amfepramone
Dosage Forms
25 mg tablets and 75 mg controlled-release tablets.
Amfepramone
Indication
Used in the management of exogenous obesity as a short-term adjunct (a few weeks) in a regimen of weight reduction based on caloric restriction.
Amfepramone
Pharmacology
Diethylpropion is a sympathomimetic stimulant drug marketed as an appetite suppressant. Chemically, it is the N,N-diethyl analog of cathinone. Its mechanism of action is similar to other appetite suppressants such as sibutramine, phentermine and dextroamphetamine.
Amfepramone
Absorption
Diethylpropion is rapidly absorbed from the GI tract after oral administration.
Amfepramone
side effects and Toxicity
The reported oral LD50 for mice is 600 mg/kg, for rats is 250 mg/kg and for dogs is 225 mg/kg. Manifestation of acute overdosage include restlessness, tremor, hyperreflexia, rapid respiration, confusion, assaultiveness, hallucinations, and panic states.
Amfepramone
Patient Information
No information avaliable
Amfepramone
Organisms Affected
Humans and other mammals