Dobesin
Brand names,
Dobesin
Analogs
Dobesin
Brand Names Mixture
Dobesin
Chemical_Formula
C13H19NO
Dobesin
RX_link
http://www.rxlist.com/cgi/generic3/diethprop.htm
Dobesin
fda sheet
Dobesin
msds (material safety sheet)
Dobesin
Synthesis Reference
No information avaliable
Dobesin
Molecular Weight
205.296 g/mol
Dobesin
Melting Point
No information avaliable
Dobesin
H2O Solubility
No information avaliable
Dobesin
State
No information avaliable
Dobesin
LogP
2.951
Dobesin
Dosage Forms
25 mg tablets and 75 mg controlled-release tablets.
Dobesin
Indication
Used in the management of exogenous obesity as a short-term adjunct (a few weeks) in a regimen of weight reduction based on caloric restriction.
Dobesin
Pharmacology
Diethylpropion is a sympathomimetic stimulant drug marketed as an appetite suppressant. Chemically, it is the N,N-diethyl analog of cathinone. Its mechanism of action is similar to other appetite suppressants such as sibutramine, phentermine and dextroamphetamine.
Dobesin
Absorption
Diethylpropion is rapidly absorbed from the GI tract after oral administration.
Dobesin
side effects and Toxicity
The reported oral LD50 for mice is 600 mg/kg, for rats is 250 mg/kg and for dogs is 225 mg/kg. Manifestation of acute overdosage include restlessness, tremor, hyperreflexia, rapid respiration, confusion, assaultiveness, hallucinations, and panic states.
Dobesin
Patient Information
No information avaliable
Dobesin
Organisms Affected
Humans and other mammals