Parabolin
Brand names,
Parabolin
Analogs
Parabolin
Brand Names Mixture
Parabolin
Chemical_Formula
C13H19NO
Parabolin
RX_link
http://www.rxlist.com/cgi/generic3/diethprop.htm
Parabolin
fda sheet
Parabolin
msds (material safety sheet)
Parabolin
Synthesis Reference
No information avaliable
Parabolin
Molecular Weight
205.296 g/mol
Parabolin
Melting Point
No information avaliable
Parabolin
H2O Solubility
No information avaliable
Parabolin
State
No information avaliable
Parabolin
LogP
2.951
Parabolin
Dosage Forms
25 mg tablets and 75 mg controlled-release tablets.
Parabolin
Indication
Used in the management of exogenous obesity as a short-term adjunct (a few weeks) in a regimen of weight reduction based on caloric restriction.
Parabolin
Pharmacology
Diethylpropion is a sympathomimetic stimulant drug marketed as an appetite suppressant. Chemically, it is the N,N-diethyl analog of cathinone. Its mechanism of action is similar to other appetite suppressants such as sibutramine, phentermine and dextroamphetamine.
Parabolin
Absorption
Diethylpropion is rapidly absorbed from the GI tract after oral administration.
Parabolin
side effects and Toxicity
The reported oral LD50 for mice is 600 mg/kg, for rats is 250 mg/kg and for dogs is 225 mg/kg. Manifestation of acute overdosage include restlessness, tremor, hyperreflexia, rapid respiration, confusion, assaultiveness, hallucinations, and panic states.
Parabolin
Patient Information
No information avaliable
Parabolin
Organisms Affected
Humans and other mammals