Amphepramone
Brand names,
Amphepramone
Analogs
Amphepramone
Brand Names Mixture
Amphepramone
Chemical_Formula
C13H19NO
Amphepramone
RX_link
http://www.rxlist.com/cgi/generic3/diethprop.htm
Amphepramone
fda sheet
Amphepramone
msds (material safety sheet)
Amphepramone
Synthesis Reference
No information avaliable
Amphepramone
Molecular Weight
205.296 g/mol
Amphepramone
Melting Point
No information avaliable
Amphepramone
H2O Solubility
No information avaliable
Amphepramone
State
No information avaliable
Amphepramone
LogP
2.951
Amphepramone
Dosage Forms
25 mg tablets and 75 mg controlled-release tablets.
Amphepramone
Indication
Used in the management of exogenous obesity as a short-term adjunct (a few weeks) in a regimen of weight reduction based on caloric restriction.
Amphepramone
Pharmacology
Diethylpropion is a sympathomimetic stimulant drug marketed as an appetite suppressant. Chemically, it is the N,N-diethyl analog of cathinone. Its mechanism of action is similar to other appetite suppressants such as sibutramine, phentermine and dextroamphetamine.
Amphepramone
Absorption
Diethylpropion is rapidly absorbed from the GI tract after oral administration.
Amphepramone
side effects and Toxicity
The reported oral LD50 for mice is 600 mg/kg, for rats is 250 mg/kg and for dogs is 225 mg/kg. Manifestation of acute overdosage include restlessness, tremor, hyperreflexia, rapid respiration, confusion, assaultiveness, hallucinations, and panic states.
Amphepramone
Patient Information
No information avaliable
Amphepramone
Organisms Affected
Humans and other mammals