Prefamone
Brand names,
Prefamone
Analogs
Prefamone
Brand Names Mixture
Prefamone
Chemical_Formula
C13H19NO
Prefamone
RX_link
http://www.rxlist.com/cgi/generic3/diethprop.htm
Prefamone
fda sheet
Prefamone
msds (material safety sheet)
Prefamone
Synthesis Reference
No information avaliable
Prefamone
Molecular Weight
205.296 g/mol
Prefamone
Melting Point
No information avaliable
Prefamone
H2O Solubility
No information avaliable
Prefamone
State
No information avaliable
Prefamone
LogP
2.951
Prefamone
Dosage Forms
25 mg tablets and 75 mg controlled-release tablets.
Prefamone
Indication
Used in the management of exogenous obesity as a short-term adjunct (a few weeks) in a regimen of weight reduction based on caloric restriction.
Prefamone
Pharmacology
Diethylpropion is a sympathomimetic stimulant drug marketed as an appetite suppressant. Chemically, it is the N,N-diethyl analog of cathinone. Its mechanism of action is similar to other appetite suppressants such as sibutramine, phentermine and dextroamphetamine.
Prefamone
Absorption
Diethylpropion is rapidly absorbed from the GI tract after oral administration.
Prefamone
side effects and Toxicity
The reported oral LD50 for mice is 600 mg/kg, for rats is 250 mg/kg and for dogs is 225 mg/kg. Manifestation of acute overdosage include restlessness, tremor, hyperreflexia, rapid respiration, confusion, assaultiveness, hallucinations, and panic states.
Prefamone
Patient Information
No information avaliable
Prefamone
Organisms Affected
Humans and other mammals