Keramin
Brand names,
Keramin
Analogs
Keramin
Brand Names Mixture
Keramin
Chemical_Formula
C13H19NO
Keramin
RX_link
http://www.rxlist.com/cgi/generic3/diethprop.htm
Keramin
fda sheet
Keramin
msds (material safety sheet)
Keramin
Synthesis Reference
No information avaliable
Keramin
Molecular Weight
205.296 g/mol
Keramin
Melting Point
No information avaliable
Keramin
H2O Solubility
No information avaliable
Keramin
State
No information avaliable
Keramin
LogP
2.951
Keramin
Dosage Forms
25 mg tablets and 75 mg controlled-release tablets.
Keramin
Indication
Used in the management of exogenous obesity as a short-term adjunct (a few weeks) in a regimen of weight reduction based on caloric restriction.
Keramin
Pharmacology
Diethylpropion is a sympathomimetic stimulant drug marketed as an appetite suppressant. Chemically, it is the N,N-diethyl analog of cathinone. Its mechanism of action is similar to other appetite suppressants such as sibutramine, phentermine and dextroamphetamine.
Keramin
Absorption
Diethylpropion is rapidly absorbed from the GI tract after oral administration.
Keramin
side effects and Toxicity
The reported oral LD50 for mice is 600 mg/kg, for rats is 250 mg/kg and for dogs is 225 mg/kg. Manifestation of acute overdosage include restlessness, tremor, hyperreflexia, rapid respiration, confusion, assaultiveness, hallucinations, and panic states.
Keramin
Patient Information
No information avaliable
Keramin
Organisms Affected
Humans and other mammals