Amphepramon
Brand names,
Amphepramon
Analogs
Amphepramon
Brand Names Mixture
Amphepramon
Chemical_Formula
C13H19NO
Amphepramon
RX_link
http://www.rxlist.com/cgi/generic3/diethprop.htm
Amphepramon
fda sheet
Amphepramon
msds (material safety sheet)
Amphepramon
Synthesis Reference
No information avaliable
Amphepramon
Molecular Weight
205.296 g/mol
Amphepramon
Melting Point
No information avaliable
Amphepramon
H2O Solubility
No information avaliable
Amphepramon
State
No information avaliable
Amphepramon
LogP
2.951
Amphepramon
Dosage Forms
25 mg tablets and 75 mg controlled-release tablets.
Amphepramon
Indication
Used in the management of exogenous obesity as a short-term adjunct (a few weeks) in a regimen of weight reduction based on caloric restriction.
Amphepramon
Pharmacology
Diethylpropion is a sympathomimetic stimulant drug marketed as an appetite suppressant. Chemically, it is the N,N-diethyl analog of cathinone. Its mechanism of action is similar to other appetite suppressants such as sibutramine, phentermine and dextroamphetamine.
Amphepramon
Absorption
Diethylpropion is rapidly absorbed from the GI tract after oral administration.
Amphepramon
side effects and Toxicity
The reported oral LD50 for mice is 600 mg/kg, for rats is 250 mg/kg and for dogs is 225 mg/kg. Manifestation of acute overdosage include restlessness, tremor, hyperreflexia, rapid respiration, confusion, assaultiveness, hallucinations, and panic states.
Amphepramon
Patient Information
No information avaliable
Amphepramon
Organisms Affected
Humans and other mammals