Amfepramon
Brand names,
Amfepramon
Analogs
Amfepramon
Brand Names Mixture
Amfepramon
Chemical_Formula
C13H19NO
Amfepramon
RX_link
http://www.rxlist.com/cgi/generic3/diethprop.htm
Amfepramon
fda sheet
Amfepramon
msds (material safety sheet)
Amfepramon
Synthesis Reference
No information avaliable
Amfepramon
Molecular Weight
205.296 g/mol
Amfepramon
Melting Point
No information avaliable
Amfepramon
H2O Solubility
No information avaliable
Amfepramon
State
No information avaliable
Amfepramon
LogP
2.951
Amfepramon
Dosage Forms
25 mg tablets and 75 mg controlled-release tablets.
Amfepramon
Indication
Used in the management of exogenous obesity as a short-term adjunct (a few weeks) in a regimen of weight reduction based on caloric restriction.
Amfepramon
Pharmacology
Diethylpropion is a sympathomimetic stimulant drug marketed as an appetite suppressant. Chemically, it is the N,N-diethyl analog of cathinone. Its mechanism of action is similar to other appetite suppressants such as sibutramine, phentermine and dextroamphetamine.
Amfepramon
Absorption
Diethylpropion is rapidly absorbed from the GI tract after oral administration.
Amfepramon
side effects and Toxicity
The reported oral LD50 for mice is 600 mg/kg, for rats is 250 mg/kg and for dogs is 225 mg/kg. Manifestation of acute overdosage include restlessness, tremor, hyperreflexia, rapid respiration, confusion, assaultiveness, hallucinations, and panic states.
Amfepramon
Patient Information
No information avaliable
Amfepramon
Organisms Affected
Humans and other mammals