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Brand names,
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Analogs
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Brand Names Mixture
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Chemical_Formula
C13H19NO
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RX_link
http://www.rxlist.com/cgi/generic3/diethprop.htm
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fda sheet
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msds (material safety sheet)
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Synthesis Reference
No information avaliable
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Molecular Weight
205.296 g/mol
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Melting Point
No information avaliable
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H2O Solubility
No information avaliable
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State
No information avaliable
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LogP
2.951
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Dosage Forms
25 mg tablets and 75 mg controlled-release tablets.
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Indication
Used in the management of exogenous obesity as a short-term adjunct (a few weeks) in a regimen of weight reduction based on caloric restriction.
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Pharmacology
Diethylpropion is a sympathomimetic stimulant drug marketed as an appetite suppressant. Chemically, it is the N,N-diethyl analog of cathinone. Its mechanism of action is similar to other appetite suppressants such as sibutramine, phentermine and dextroamphetamine.
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Absorption
Diethylpropion is rapidly absorbed from the GI tract after oral administration.
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side effects and Toxicity
The reported oral LD50 for mice is 600 mg/kg, for rats is 250 mg/kg and for dogs is 225 mg/kg. Manifestation of acute overdosage include restlessness, tremor, hyperreflexia, rapid respiration, confusion, assaultiveness, hallucinations, and panic states.
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Patient Information
No information avaliable
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Organisms Affected
Humans and other mammals