Magrene
Brand names,
Magrene
Analogs
Magrene
Brand Names Mixture
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Chemical_Formula
C13H19NO
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RX_link
http://www.rxlist.com/cgi/generic3/diethprop.htm
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fda sheet
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msds (material safety sheet)
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Synthesis Reference
No information avaliable
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Molecular Weight
205.296 g/mol
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Melting Point
No information avaliable
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H2O Solubility
No information avaliable
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State
No information avaliable
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LogP
2.951
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Dosage Forms
25 mg tablets and 75 mg controlled-release tablets.
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Indication
Used in the management of exogenous obesity as a short-term adjunct (a few weeks) in a regimen of weight reduction based on caloric restriction.
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Pharmacology
Diethylpropion is a sympathomimetic stimulant drug marketed as an appetite suppressant. Chemically, it is the N,N-diethyl analog of cathinone. Its mechanism of action is similar to other appetite suppressants such as sibutramine, phentermine and dextroamphetamine.
Magrene
Absorption
Diethylpropion is rapidly absorbed from the GI tract after oral administration.
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side effects and Toxicity
The reported oral LD50 for mice is 600 mg/kg, for rats is 250 mg/kg and for dogs is 225 mg/kg. Manifestation of acute overdosage include restlessness, tremor, hyperreflexia, rapid respiration, confusion, assaultiveness, hallucinations, and panic states.
Magrene
Patient Information
No information avaliable
Magrene
Organisms Affected
Humans and other mammals