Amfepramone Hydrochloride
Brand names,
Amfepramone Hydrochloride
Analogs
Amfepramone Hydrochloride
Brand Names Mixture
Amfepramone Hydrochloride
Chemical_Formula
C13H19NO
Amfepramone Hydrochloride
RX_link
http://www.rxlist.com/cgi/generic3/diethprop.htm
Amfepramone Hydrochloride
fda sheet
Amfepramone Hydrochloride
msds (material safety sheet)
Amfepramone Hydrochloride
Synthesis Reference
No information avaliable
Amfepramone Hydrochloride
Molecular Weight
205.296 g/mol
Amfepramone Hydrochloride
Melting Point
No information avaliable
Amfepramone Hydrochloride
H2O Solubility
No information avaliable
Amfepramone Hydrochloride
State
No information avaliable
Amfepramone Hydrochloride
LogP
2.951
Amfepramone Hydrochloride
Dosage Forms
25 mg tablets and 75 mg controlled-release tablets.
Amfepramone Hydrochloride
Indication
Used in the management of exogenous obesity as a short-term adjunct (a few weeks) in a regimen of weight reduction based on caloric restriction.
Amfepramone Hydrochloride
Pharmacology
Diethylpropion is a sympathomimetic stimulant drug marketed as an appetite suppressant. Chemically, it is the N,N-diethyl analog of cathinone. Its mechanism of action is similar to other appetite suppressants such as sibutramine, phentermine and dextroamphetamine.
Amfepramone Hydrochloride
Absorption
Diethylpropion is rapidly absorbed from the GI tract after oral administration.
Amfepramone Hydrochloride
side effects and Toxicity
The reported oral LD50 for mice is 600 mg/kg, for rats is 250 mg/kg and for dogs is 225 mg/kg. Manifestation of acute overdosage include restlessness, tremor, hyperreflexia, rapid respiration, confusion, assaultiveness, hallucinations, and panic states.
Amfepramone Hydrochloride
Patient Information
No information avaliable
Amfepramone Hydrochloride
Organisms Affected
Humans and other mammals