Roxosul Tablets

Roxosul Tablets Brand names, Roxosul Tablets Analogs

Roxosul Tablets Brand Names Mixture

Pediazole (Erythromycin (Erythromycin Ethylsuccinate) + Sulfisoxazole Acetyl)
Renazone Plus Tab (Ammonium Chloride + Atropine Sulfate + Hyoscyamine Hydrobromide + Scopolamine Hydrobromide + Sulfisoxazole)

Roxosul Tablets Chemical_Formula

C₁₁H₁₃N₃O₃S

Roxosul Tablets RX_link

No information avaliable

Roxosul Tablets fda sheet

Roxosul Tablets msds (material safety sheet)

Roxosul_Tablets MSDS

Roxosul Tablets Synthesis Reference

H. M. Wuest, M. Hoffer, U.S. pat. 2,430,094 (1947 to Hoffmann-La Roche)

Roxosul Tablets Molecular Weight

267.305 g/mol

Roxosul Tablets Melting Point

194 ^oC

Roxosul Tablets H₂O Solubility

0.13 mg/ml (25 oC)

Roxosul Tablets State

Solid

Roxosul Tablets LogP

2.569

Roxosul Tablets Dosage Forms

Tablet; Oral suspension; Eye drops

Roxosul Tablets Indication

Treatment of severe, repeated, or long-lasting urinary tract infections, meningococcal meningitis, acute otitis media, trachoma, inclusion conjunctivitis, nocardiosis, chancroid, toxoplasmosis, malaria and other bacterial infections.

Roxosul Tablets Pharmacology

Sulfisoxazole is a sulfonamide antibiotic. The sulfonamides are synthetic bacteriostatic antibiotics with a wide spectrum against most gram-positive and many gram-negative organisms. However, many strains of an individual species may be resistant. Sulfonamides inhibit multiplication of bacteria by acting as competitive inhibitors of p-aminobenzoic acid in the folic acid metabolism cycle. Bacterial sensitivity is the same for the various sulfonamides, and resistance to one sulfonamide indicates resistance to all. Most sulfonamides are readily absorbed orally. However, parenteral administration is difficult, since the soluble sulfonamide salts are highly alkaline and irritating to the tissues. The sulfonamides are widely distributed throughout all tissues. High levels are achieved in pleural, peritoneal, synovial, and ocular fluids. Although these drugs are no longer used to treat meningitis, CSF levels are high in meningeal infections. Their antibacterial action is inhibited by pus.

Roxosul Tablets Absorption