Azo Gantrisin

Azo Gantrisin Brand names, Azo Gantrisin Analogs

Azo Gantrisin Brand Names Mixture

Pediazole (Erythromycin (Erythromycin Ethylsuccinate) + Sulfisoxazole Acetyl)
Renazone Plus Tab (Ammonium Chloride + Atropine Sulfate + Hyoscyamine Hydrobromide + Scopolamine Hydrobromide + Sulfisoxazole)

Azo Gantrisin Chemical_Formula

C₁₁H₁₃N₃O₃S

Azo Gantrisin RX_link

No information avaliable

Azo Gantrisin fda sheet

Azo Gantrisin msds (material safety sheet)

Azo_Gantrisin MSDS

Azo Gantrisin Synthesis Reference

H. M. Wuest, M. Hoffer, U.S. pat. 2,430,094 (1947 to Hoffmann-La Roche)

Azo Gantrisin Molecular Weight

267.305 g/mol

Azo Gantrisin Melting Point

194 ^oC

Azo Gantrisin H₂O Solubility

0.13 mg/ml (25 oC)

Azo Gantrisin State

Solid

Azo Gantrisin LogP

2.569

Azo Gantrisin Dosage Forms

Tablet; Oral suspension; Eye drops

Azo Gantrisin Indication

Treatment of severe, repeated, or long-lasting urinary tract infections, meningococcal meningitis, acute otitis media, trachoma, inclusion conjunctivitis, nocardiosis, chancroid, toxoplasmosis, malaria and other bacterial infections.

Azo Gantrisin Pharmacology

Sulfisoxazole is a sulfonamide antibiotic. The sulfonamides are synthetic bacteriostatic antibiotics with a wide spectrum against most gram-positive and many gram-negative organisms. However, many strains of an individual species may be resistant. Sulfonamides inhibit multiplication of bacteria by acting as competitive inhibitors of p-aminobenzoic acid in the folic acid metabolism cycle. Bacterial sensitivity is the same for the various sulfonamides, and resistance to one sulfonamide indicates resistance to all. Most sulfonamides are readily absorbed orally. However, parenteral administration is difficult, since the soluble sulfonamide salts are highly alkaline and irritating to the tissues. The sulfonamides are widely distributed throughout all tissues. High levels are achieved in pleural, peritoneal, synovial, and ocular fluids. Although these drugs are no longer used to treat meningitis, CSF levels are high in meningeal infections. Their antibacterial action is inhibited by pus.

Azo Gantrisin Absorption