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Barazae Brand names, Barazae Analogs

Barazae Brand Names Mixture

  • Pediazole (Erythromycin (Erythromycin Ethylsuccinate) + Sulfisoxazole Acetyl)
  • Renazone Plus Tab (Ammonium Chloride + Atropine Sulfate + Hyoscyamine Hydrobromide + Scopolamine Hydrobromide + Sulfisoxazole)

Barazae Chemical_Formula


Barazae RX_link

No information avaliable

Barazae fda sheet

Barazae msds (material safety sheet)

Barazae MSDS

Barazae Synthesis Reference

H. M. Wuest, M. Hoffer, U.S. pat. 2,430,094 (1947 to Hoffmann-La Roche)

Barazae Molecular Weight

267.305 g/mol

Barazae Melting Point

194 oC

Barazae H2O Solubility

0.13 mg/ml (25 oC)

Barazae State


Barazae LogP


Barazae Dosage Forms

Tablet; Oral suspension; Eye drops

Barazae Indication

Treatment of severe, repeated, or long-lasting urinary tract infections, meningococcal meningitis, acute otitis media, trachoma, inclusion conjunctivitis, nocardiosis, chancroid, toxoplasmosis, malaria and other bacterial infections.

Barazae Pharmacology

Sulfisoxazole is a sulfonamide antibiotic. The sulfonamides are synthetic bacteriostatic antibiotics with a wide spectrum against most gram-positive and many gram-negative organisms. However, many strains of an individual species may be resistant. Sulfonamides inhibit multiplication of bacteria by acting as competitive inhibitors of p-aminobenzoic acid in the folic acid metabolism cycle. Bacterial sensitivity is the same for the various sulfonamides, and resistance to one sulfonamide indicates resistance to all. Most sulfonamides are readily absorbed orally. However, parenteral administration is difficult, since the soluble sulfonamide salts are highly alkaline and irritating to the tissues. The sulfonamides are widely distributed throughout all tissues. High levels are achieved in pleural, peritoneal, synovial, and ocular fluids. Although these drugs are no longer used to treat meningitis, CSF levels are high in meningeal infections. Their antibacterial action is inhibited by pus.

Barazae Absorption

No information avaliable

Barazae side effects and Toxicity

LD50=6800 mg/kg (Orally in mice)

Barazae Patient Information

Barazae Organisms Affected

Enteric bacteria and other eubacteria