Amidoxal en es it fr

Amidoxal Brand names, Amidoxal Analogs

Amidoxal Brand Names Mixture

  • Pediazole (Erythromycin (Erythromycin Ethylsuccinate) + Sulfisoxazole Acetyl)
  • Renazone Plus Tab (Ammonium Chloride + Atropine Sulfate + Hyoscyamine Hydrobromide + Scopolamine Hydrobromide + Sulfisoxazole)

Amidoxal Chemical_Formula


Amidoxal RX_link

No information avaliable

Amidoxal fda sheet

Amidoxal msds (material safety sheet)

Amidoxal MSDS

Amidoxal Synthesis Reference

H. M. Wuest, M. Hoffer, U.S. pat. 2,430,094 (1947 to Hoffmann-La Roche)

Amidoxal Molecular Weight

267.305 g/mol

Amidoxal Melting Point

194 oC

Amidoxal H2O Solubility

0.13 mg/ml (25 oC)

Amidoxal State


Amidoxal LogP


Amidoxal Dosage Forms

Tablet; Oral suspension; Eye drops

Amidoxal Indication

Treatment of severe, repeated, or long-lasting urinary tract infections, meningococcal meningitis, acute otitis media, trachoma, inclusion conjunctivitis, nocardiosis, chancroid, toxoplasmosis, malaria and other bacterial infections.

Amidoxal Pharmacology

Sulfisoxazole is a sulfonamide antibiotic. The sulfonamides are synthetic bacteriostatic antibiotics with a wide spectrum against most gram-positive and many gram-negative organisms. However, many strains of an individual species may be resistant. Sulfonamides inhibit multiplication of bacteria by acting as competitive inhibitors of p-aminobenzoic acid in the folic acid metabolism cycle. Bacterial sensitivity is the same for the various sulfonamides, and resistance to one sulfonamide indicates resistance to all. Most sulfonamides are readily absorbed orally. However, parenteral administration is difficult, since the soluble sulfonamide salts are highly alkaline and irritating to the tissues. The sulfonamides are widely distributed throughout all tissues. High levels are achieved in pleural, peritoneal, synovial, and ocular fluids. Although these drugs are no longer used to treat meningitis, CSF levels are high in meningeal infections. Their antibacterial action is inhibited by pus.

Amidoxal Absorption

No information avaliable

Amidoxal side effects and Toxicity

LD50=6800 mg/kg (Orally in mice)

Amidoxal Patient Information

Amidoxal Organisms Affected

Enteric bacteria and other eubacteria