Retolen
Retolen Brand names, Retolen Analogs
Retolen Brand Names Mixture
- No information avaliable
Retolen Chemical_Formula
C28H31FN4O
Retolen RX_link
http://www.rxlist.com/cgi/generic/astem.htm
Retolen fda sheet
Retolen msds (material safety sheet)
Retolen Synthesis Reference
F. Janssens et al., U.S. Pat. 4,219,559 (1980)
Retolen Molecular Weight
458.571 g/mol
Retolen Melting Point
149.1oC
Retolen H2O Solubility
432 mg/L
Retolen State
Solid
Retolen LogP
5.572
Retolen Dosage Forms
Suspension; Tablet
Retolen Indication
For the relief of symptoms associated with seasonal allergic rhinitis and chronic idiopathic urticaria.
Retolen Pharmacology
Astemizole, an H1-receptor antagonist, is similar in structure to terfenadine and haloperidol, a butyrophenone antipsychotic. It has anticholinergic (atropine-like) and antipruritic effects.
Retolen Absorption
Rapidly absorbed from the gastrointestinal tract.
Retolen side effects and Toxicity
LD50=2052mg/kg in mice
Retolen Patient Information
Retolen Organisms Affected
Humans and other mammals
