Histaminos
Brand names,
Histaminos
Analogs
Histaminos
Brand Names Mixture
Histaminos
Chemical_Formula
C28H31FN4O
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RX_link
http://www.rxlist.com/cgi/generic/astem.htm
Histaminos
fda sheet
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msds (material safety sheet)
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Synthesis Reference
F. Janssens et al., U.S. Pat. 4,219,559 (1980)
Histaminos
Molecular Weight
458.571 g/mol
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Melting Point
149.1oC
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H2O Solubility
432 mg/L
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State
Solid
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LogP
5.572
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Dosage Forms
Suspension; Tablet
Histaminos
Indication
For the relief of symptoms associated with seasonal allergic rhinitis and chronic idiopathic urticaria.
Histaminos
Pharmacology
Astemizole, an H1-receptor antagonist, is similar in structure to terfenadine and haloperidol, a butyrophenone antipsychotic. It has anticholinergic (atropine-like) and antipruritic effects.
Histaminos
Absorption
Rapidly absorbed from the gastrointestinal tract.
Histaminos
side effects and Toxicity
LD50=2052mg/kg in mice
Histaminos
Patient Information
Histaminos
Organisms Affected
Humans and other mammals