Astemison
Brand names,
Astemison
Analogs
Astemison
Brand Names Mixture
Astemison
Chemical_Formula
C28H31FN4O
Astemison
RX_link
http://www.rxlist.com/cgi/generic/astem.htm
Astemison
fda sheet
Astemison
msds (material safety sheet)
Astemison
Synthesis Reference
F. Janssens et al., U.S. Pat. 4,219,559 (1980)
Astemison
Molecular Weight
458.571 g/mol
Astemison
Melting Point
149.1oC
Astemison
H2O Solubility
432 mg/L
Astemison
State
Solid
Astemison
LogP
5.572
Astemison
Dosage Forms
Suspension; Tablet
Astemison
Indication
For the relief of symptoms associated with seasonal allergic rhinitis and chronic idiopathic urticaria.
Astemison
Pharmacology
Astemizole, an H1-receptor antagonist, is similar in structure to terfenadine and haloperidol, a butyrophenone antipsychotic. It has anticholinergic (atropine-like) and antipruritic effects.
Astemison
Absorption
Rapidly absorbed from the gastrointestinal tract.
Astemison
side effects and Toxicity
LD50=2052mg/kg in mice
Astemison
Patient Information
Astemison
Organisms Affected
Humans and other mammals