Nono-Nastizol A
Brand names,
Nono-Nastizol A
Analogs
Nono-Nastizol A
Brand Names Mixture
Nono-Nastizol A
Chemical_Formula
C28H31FN4O
Nono-Nastizol A
RX_link
http://www.rxlist.com/cgi/generic/astem.htm
Nono-Nastizol A
fda sheet
Nono-Nastizol A
msds (material safety sheet)
Nono-Nastizol A
Synthesis Reference
F. Janssens et al., U.S. Pat. 4,219,559 (1980)
Nono-Nastizol A
Molecular Weight
458.571 g/mol
Nono-Nastizol A
Melting Point
149.1oC
Nono-Nastizol A
H2O Solubility
432 mg/L
Nono-Nastizol A
State
Solid
Nono-Nastizol A
LogP
5.572
Nono-Nastizol A
Dosage Forms
Suspension; Tablet
Nono-Nastizol A
Indication
For the relief of symptoms associated with seasonal allergic rhinitis and chronic idiopathic urticaria.
Nono-Nastizol A
Pharmacology
Astemizole, an H1-receptor antagonist, is similar in structure to terfenadine and haloperidol, a butyrophenone antipsychotic. It has anticholinergic (atropine-like) and antipruritic effects.
Nono-Nastizol A
Absorption
Rapidly absorbed from the gastrointestinal tract.
Nono-Nastizol A
side effects and Toxicity
LD50=2052mg/kg in mice
Nono-Nastizol A
Patient Information
Nono-Nastizol A
Organisms Affected
Humans and other mammals