Metodik
Metodik Brand names, Metodik Analogs
Metodik Brand Names Mixture
- No information avaliable
Metodik Chemical_Formula
C28H31FN4O
Metodik RX_link
http://www.rxlist.com/cgi/generic/astem.htm
Metodik fda sheet
Metodik msds (material safety sheet)
Metodik Synthesis Reference
F. Janssens et al., U.S. Pat. 4,219,559 (1980)
Metodik Molecular Weight
458.571 g/mol
Metodik Melting Point
149.1oC
Metodik H2O Solubility
432 mg/L
Metodik State
Solid
Metodik LogP
5.572
Metodik Dosage Forms
Suspension; Tablet
Metodik Indication
For the relief of symptoms associated with seasonal allergic rhinitis and chronic idiopathic urticaria.
Metodik Pharmacology
Astemizole, an H1-receptor antagonist, is similar in structure to terfenadine and haloperidol, a butyrophenone antipsychotic. It has anticholinergic (atropine-like) and antipruritic effects.
Metodik Absorption
Rapidly absorbed from the gastrointestinal tract.
Metodik side effects and Toxicity
LD50=2052mg/kg in mice
Metodik Patient Information
Metodik Organisms Affected
Humans and other mammals
