Paralergin
Brand names,
Paralergin
Analogs
Paralergin
Brand Names Mixture
Paralergin
Chemical_Formula
C28H31FN4O
Paralergin
RX_link
http://www.rxlist.com/cgi/generic/astem.htm
Paralergin
fda sheet
Paralergin
msds (material safety sheet)
Paralergin
Synthesis Reference
F. Janssens et al., U.S. Pat. 4,219,559 (1980)
Paralergin
Molecular Weight
458.571 g/mol
Paralergin
Melting Point
149.1oC
Paralergin
H2O Solubility
432 mg/L
Paralergin
State
Solid
Paralergin
LogP
5.572
Paralergin
Dosage Forms
Suspension; Tablet
Paralergin
Indication
For the relief of symptoms associated with seasonal allergic rhinitis and chronic idiopathic urticaria.
Paralergin
Pharmacology
Astemizole, an H1-receptor antagonist, is similar in structure to terfenadine and haloperidol, a butyrophenone antipsychotic. It has anticholinergic (atropine-like) and antipruritic effects.
Paralergin
Absorption
Rapidly absorbed from the gastrointestinal tract.
Paralergin
side effects and Toxicity
LD50=2052mg/kg in mice
Paralergin
Patient Information
Paralergin
Organisms Affected
Humans and other mammals