Histamen
Brand names,
Histamen
Analogs
Histamen
Brand Names Mixture
Histamen
Chemical_Formula
C28H31FN4O
Histamen
RX_link
http://www.rxlist.com/cgi/generic/astem.htm
Histamen
fda sheet
Histamen
msds (material safety sheet)
Histamen
Synthesis Reference
F. Janssens et al., U.S. Pat. 4,219,559 (1980)
Histamen
Molecular Weight
458.571 g/mol
Histamen
Melting Point
149.1oC
Histamen
H2O Solubility
432 mg/L
Histamen
State
Solid
Histamen
LogP
5.572
Histamen
Dosage Forms
Suspension; Tablet
Histamen
Indication
For the relief of symptoms associated with seasonal allergic rhinitis and chronic idiopathic urticaria.
Histamen
Pharmacology
Astemizole, an H1-receptor antagonist, is similar in structure to terfenadine and haloperidol, a butyrophenone antipsychotic. It has anticholinergic (atropine-like) and antipruritic effects.
Histamen
Absorption
Rapidly absorbed from the gastrointestinal tract.
Histamen
side effects and Toxicity
LD50=2052mg/kg in mice
Histamen
Patient Information
Histamen
Organisms Affected
Humans and other mammals