Laridal
Brand names,
Laridal
Analogs
Laridal
Brand Names Mixture
Laridal
Chemical_Formula
C28H31FN4O
Laridal
RX_link
http://www.rxlist.com/cgi/generic/astem.htm
Laridal
fda sheet
Laridal
msds (material safety sheet)
Laridal
Synthesis Reference
F. Janssens et al., U.S. Pat. 4,219,559 (1980)
Laridal
Molecular Weight
458.571 g/mol
Laridal
Melting Point
149.1oC
Laridal
H2O Solubility
432 mg/L
Laridal
State
Solid
Laridal
LogP
5.572
Laridal
Dosage Forms
Suspension; Tablet
Laridal
Indication
For the relief of symptoms associated with seasonal allergic rhinitis and chronic idiopathic urticaria.
Laridal
Pharmacology
Astemizole, an H1-receptor antagonist, is similar in structure to terfenadine and haloperidol, a butyrophenone antipsychotic. It has anticholinergic (atropine-like) and antipruritic effects.
Laridal
Absorption
Rapidly absorbed from the gastrointestinal tract.
Laridal
side effects and Toxicity
LD50=2052mg/kg in mice
Laridal
Patient Information
Laridal
Organisms Affected
Humans and other mammals