Alermizol
Brand names,
Alermizol
Analogs
Alermizol
Brand Names Mixture
Alermizol
Chemical_Formula
C28H31FN4O
Alermizol
RX_link
http://www.rxlist.com/cgi/generic/astem.htm
Alermizol
fda sheet
Alermizol
msds (material safety sheet)
Alermizol
Synthesis Reference
F. Janssens et al., U.S. Pat. 4,219,559 (1980)
Alermizol
Molecular Weight
458.571 g/mol
Alermizol
Melting Point
149.1oC
Alermizol
H2O Solubility
432 mg/L
Alermizol
State
Solid
Alermizol
LogP
5.572
Alermizol
Dosage Forms
Suspension; Tablet
Alermizol
Indication
For the relief of symptoms associated with seasonal allergic rhinitis and chronic idiopathic urticaria.
Alermizol
Pharmacology
Astemizole, an H1-receptor antagonist, is similar in structure to terfenadine and haloperidol, a butyrophenone antipsychotic. It has anticholinergic (atropine-like) and antipruritic effects.
Alermizol
Absorption
Rapidly absorbed from the gastrointestinal tract.
Alermizol
side effects and Toxicity
LD50=2052mg/kg in mice
Alermizol
Patient Information
Alermizol
Organisms Affected
Humans and other mammals