Pridesia
Pridesia Brand names, Pridesia Analogs
Pridesia Brand Names Mixture
- No information avaliable
Pridesia Chemical_Formula
C23H29ClFN3O4
Pridesia RX_link
http://www.rxlist.com/cgi/generic/cisap.htm
Pridesia fda sheet
Pridesia msds (material safety sheet)
Pridesia Synthesis Reference
No information avaliable
Pridesia Molecular Weight
465.945 g/mol
Pridesia Melting Point
110 oC
Pridesia H2O Solubility
2.71 mg/L
Pridesia State
Solid
Pridesia LogP
3.802
Pridesia Dosage Forms
Suspension; Tablet
Pridesia Indication
For the symptomatic treatment of adult patients with nocturnal heartburn due to gastroesophageal reflux disease.
Pridesia Pharmacology
Cisapride is a parasympathomimetic which acts as a serotonin 5-HT4 agonist. Stimulation of the serotonin receptors increases acetylcholine release in the enteric nervous system. Cisapride stimulates motility of the upper gastrointestinal tract without stimulating gastric, biliary, or pancreatic secretions. Cisapride increases the tone and amplitude of gastric (especially antral) contractions, relaxes the pyloric sphincter and the duodenal bulb, and increases peristalsis of the duodenum and jejunum resulting in accelerated gastric emptying and intestinal transit. It increases the resting tone of the lower esophageal sphincter. It has little, if any, effect on the motility of the colon or gallbladder. Cisapride does not induce muscarinic or nicotinic receptor stimulation, nor does it inhibit acetylcholinesterase activity.
Pridesia Absorption
Cisapride is rapidly absorbed after oral administration, with an absolute bioavailability of 35-40%.
Pridesia side effects and Toxicity
No information avaliable
Pridesia Patient Information
No information avaliable
Pridesia Organisms Affected
Humans and other mammals
