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Syspride Brand names, Syspride Analogs

Syspride Brand Names Mixture

  • No information avaliable

Syspride Chemical_Formula


Syspride RX_link

Syspride fda sheet

Syspride msds (material safety sheet)

Syspride MSDS

Syspride Synthesis Reference

No information avaliable

Syspride Molecular Weight

465.945 g/mol

Syspride Melting Point

110 oC

Syspride H2O Solubility

2.71 mg/L

Syspride State


Syspride LogP


Syspride Dosage Forms

Suspension; Tablet

Syspride Indication

For the symptomatic treatment of adult patients with nocturnal heartburn due to gastroesophageal reflux disease.

Syspride Pharmacology

Cisapride is a parasympathomimetic which acts as a serotonin 5-HT4 agonist. Stimulation of the serotonin receptors increases acetylcholine release in the enteric nervous system. Cisapride stimulates motility of the upper gastrointestinal tract without stimulating gastric, biliary, or pancreatic secretions. Cisapride increases the tone and amplitude of gastric (especially antral) contractions, relaxes the pyloric sphincter and the duodenal bulb, and increases peristalsis of the duodenum and jejunum resulting in accelerated gastric emptying and intestinal transit. It increases the resting tone of the lower esophageal sphincter. It has little, if any, effect on the motility of the colon or gallbladder. Cisapride does not induce muscarinic or nicotinic receptor stimulation, nor does it inhibit acetylcholinesterase activity.

Syspride Absorption

Cisapride is rapidly absorbed after oral administration, with an absolute bioavailability of 35-40%.

Syspride side effects and Toxicity

No information avaliable

Syspride Patient Information

No information avaliable

Syspride Organisms Affected

Humans and other mammals