Enteropride
Enteropride Brand names, Enteropride Analogs
Enteropride Brand Names Mixture
- No information avaliable
Enteropride Chemical_Formula
C23H29ClFN3O4
Enteropride RX_link
http://www.rxlist.com/cgi/generic/cisap.htm
Enteropride fda sheet
Enteropride msds (material safety sheet)
Enteropride Synthesis Reference
No information avaliable
Enteropride Molecular Weight
465.945 g/mol
Enteropride Melting Point
110 oC
Enteropride H2O Solubility
2.71 mg/L
Enteropride State
Solid
Enteropride LogP
3.802
Enteropride Dosage Forms
Suspension; Tablet
Enteropride Indication
For the symptomatic treatment of adult patients with nocturnal heartburn due to gastroesophageal reflux disease.
Enteropride Pharmacology
Cisapride is a parasympathomimetic which acts as a serotonin 5-HT4 agonist. Stimulation of the serotonin receptors increases acetylcholine release in the enteric nervous system. Cisapride stimulates motility of the upper gastrointestinal tract without stimulating gastric, biliary, or pancreatic secretions. Cisapride increases the tone and amplitude of gastric (especially antral) contractions, relaxes the pyloric sphincter and the duodenal bulb, and increases peristalsis of the duodenum and jejunum resulting in accelerated gastric emptying and intestinal transit. It increases the resting tone of the lower esophageal sphincter. It has little, if any, effect on the motility of the colon or gallbladder. Cisapride does not induce muscarinic or nicotinic receptor stimulation, nor does it inhibit acetylcholinesterase activity.
Enteropride Absorption
Cisapride is rapidly absorbed after oral administration, with an absolute bioavailability of 35-40%.
Enteropride side effects and Toxicity
No information avaliable
Enteropride Patient Information
No information avaliable
Enteropride Organisms Affected
Humans and other mammals
